Neural feedback is insufficient in preterm infants during neurally adjusted ventilatory assist

Objectives To investigate the effects of changing assistance levels on respiratory patterns, including peak inspiratory pressure (PIP), overassistance, work of breathing, and discomfort in preterm infants during neurally adjusted ventilatory assist (NAVA). Working hypothesis Once the lungs reach optimal inflation, negative feedback suppresses neural respiratory drive and therefore, the electrical activity of the diaphragm (Edi) such that the...