MON-619 The Direct Stimulatory Effect of Thyroid Hormone Against Plasma Brain Natriuretic Peptide in Health Check-Up Participants: Cross-Sectional and Longitudinal Studies

Background: Circulating levels of thyroid hormone (TH) and TSH may not always reflect TH activity in specific peripheral tissues. Although the heart is one of the major target organs for TH, the tissue-specific circulating markers of TH activity have not been characterized. Therefore, we investigated the independent effects of TH status on plasma brain natriuretic peptide (BNP) concentrations in a large number of health check-up participants....