SAT-229 HCG Alpha Might Supplant TSH during the Fetal Period to Promote Brain Development

It is widely agreed that adequate maternal thyroid hormone is necessary for proper brain development. The role of the fetal placenta in ensuring the production and delivery of thyroid hormone during fetal brain development is less well understood. We hypothesized that the placenta ‘hijacks’ the maternal thyroid in early pregnancy to ensure adequate thyroid hormone, and either or both endocrine systems are vulnerable to perturbation by phthalate...