Review paper
Aptamers as Therapeutic Agents: Has the Initial Euphoria Subsided?
Abstract
Aptamers are synthetic DNA or RNA oligonucleotide ligands with great potential for therapeutic applications. A vast number of disease-related targets have been used to identify agonistic, antagonistic, or inhibitory aptamers, or aptamer-based targeting ligands. However, only a few aptamers have reached late-stage clinical trials so far and the commercial infrastructure is still far behind that of other therapeutic agents such as monoclonal...
Paper Details
Title
Aptamers as Therapeutic Agents: Has the Initial Euphoria Subsided?
Published Date
Apr 29, 2019
Volume
23
Issue
3
Pages
301 - 309
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