Hairless as a novel component of the Notch signaling pathway

Pages: 621367
Published: Apr 29, 2019
Abstract
null Suppressor of Hairless [Su(H)], the transcription factor at the end of the Notch pathway in Drosophila, utilizes the Hairless protein to recruit two co-repressors, Groucho (Gro) and C-terminal Binding Protein (CtBP), indirectly. Hairless is present only in the Pancrustacea, raising the question of how Su(H) in other protostomes gains repressive function. We show that Su(H) from a wide array of arthropods, molluscs, and annelids includes...
Paper Details
Title
Hairless as a novel component of the Notch signaling pathway
Published Date
Apr 29, 2019
Journal
Pages
621367
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