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Dietary total fat, fatty acids intake, and risk of cardiovascular disease: a dose-response meta-analysis of cohort studies

Published on Apr 6, 2019in Lipids in Health and Disease 2.66
· DOI :10.1186/s12944-019-1035-2
Yongjian Zhu (Zhengzhou University), Yacong Bo (Zhengzhou University), Yanhua Liu (Zhengzhou University)
Background Several epidemiological studies have investigated the association between dietary fat intake and cardiovascular disease. However, dietary recommendations based on systematic review and meta-analysis might be more credible.
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Published on Aug 1, 2018in European Journal of Nutrition 4.42
Rafael Longhi2
Estimated H-index: 2
(UFRGS: Universidade Federal do Rio Grande do Sul),
Roberto Farina de Almeida9
Estimated H-index: 9
(UFRGS: Universidade Federal do Rio Grande do Sul)
+ 4 AuthorsDiogo O. Souza59
Estimated H-index: 59
(UFRGS: Universidade Federal do Rio Grande do Sul)
Purpose Previously showed that dietary trans fatty acids (TFAs) may cause systemic inflammation and affect the central nervous system (CNS) in Wistar rats by increased levels of cytokines in the cerebrospinal fluid (CSF) and serum (Longhi et al. Eur J Nutr 56(3):1003–1016, 1). Here, we aimed to clarifying the impact of diets with different TFA concentrations on cerebral tissue, focusing on hippocampus and cortex and behavioral performance.
2 Citations Source Cite
Published on Apr 1, 2018in The Lancet 53.25
Jim Mann65
Estimated H-index: 65
(University of Otago),
Joerg J. Meerpohl33
Estimated H-index: 33
(University of Freiburg)
+ 2 AuthorsLisa Te Morenga9
Estimated H-index: 9
(University of Otago)
2 Citations Source Cite
Published on Nov 1, 2017in The Lancet 53.25
Mahshid Dehghan22
Estimated H-index: 22
(Population Health Research Institute),
Andrew Mente30
Estimated H-index: 30
(McMaster University)
+ 352 AuthorsAnders H. Rosengren84
Estimated H-index: 84
(University of Gothenburg)
Summary Background The relationship between macronutrients and cardiovascular disease and mortality is controversial. Most available data are from European and North American populations where nutrition excess is more likely, so their applicability to other populations is unclear. Methods The Prospective Urban Rural Epidemiology (PURE) study is a large, epidemiological cohort study of individuals aged 35–70 years (enrolled between Jan 1, 2003, and March 31, 2013) in 18 countries with a median fo...
168 Citations Source Cite
Published on Oct 1, 2017in American Journal of Cardiology 3.17
Pia Thisted Dinesen2
Estimated H-index: 2
(AAU: Aalborg University),
Albert Marni Joensen11
Estimated H-index: 11
(AAU: Aalborg University)
+ 4 AuthorsKim Overvad111
Estimated H-index: 111
(AU: Aarhus University)
The aim of the present study was to explore substitution of intake of saturated fatty acids (FAs) with monounsaturated and polyunsaturated FAs and incident atrial fibrillation (AF) in men and women. A total of 57,053 Danish participants aged 50 to 64 years were enrolled in the Diet, Cancer and Health cohort study in 1993 to 1997 and completed a semiquantitative food frequency questionnaire at baseline. Follow-up was registry-based and data were analyzed using Cox proportional hazards regression....
2 Citations Source Cite
Published on Sep 1, 2017in Nutrition Metabolism and Cardiovascular Diseases 3.32
Ivonne Sluijs28
Estimated H-index: 28
(UU: Utrecht University),
Jaike Praagman3
Estimated H-index: 3
(UU: Utrecht University)
+ 2 AuthorsY. T. van der Schouw88
Estimated H-index: 88
(UU: Utrecht University)
Abstract Background and aims The fluidity of dietary fatty acids consumed has been suggested to inversely affect coronary heart disease (CHD) risk. Lipophilic index (LI) represents overall fluidity of the dietary fatty acid profile. Lipophilic load (LL) represents a combination of overall fluidity and absolute intake of dietary fatty acids. We investigated the relations of dietary LI and LL with risk of CHD and ischemic stroke (iStroke). Methods and results We used data from the prospective EPIC...
3 Citations Source Cite
Published on Jul 3, 2017in Critical Reviews in Food Science and Nutrition 6.20
Sarah F. Brennan5
Estimated H-index: 5
('QUB': Queen's University Belfast),
Jayne V. Woodside38
Estimated H-index: 38
('QUB': Queen's University Belfast)
+ 2 AuthorsMarie M. Cantwell31
Estimated H-index: 31
('QUB': Queen's University Belfast)
ABSTRACTBackground: The influence of dietary fat upon breast cancer mortality remains largely understudied despite extensive investigation into its influence upon breast cancer risk. Objective: To conduct meta-analyses of studies to clarify the association between dietary fat and breast cancer mortality. Design: MEDLINE and EMBASE were searched for relevant articles published up to March 2012. Risk of all-cause or breast-cancer-specific death was evaluated by combining multivariable adjusted est...
10 Citations Source Cite
Published on Mar 1, 2017in Nature Reviews Cardiology 15.16
Neil Ruparelia15
Estimated H-index: 15
Joshua T. Chai8
Estimated H-index: 8
+ 1 AuthorsRobin P. Choudhury40
Estimated H-index: 40
Inflammatory processes are central to the development and complications of atherosclerosis and acute myocardial infarction. In this Review, Ruparelia et al. summarize the inflammatory pathways involved in these cardiovascular diseases, highlight contemporary techniques to characterize and quantify inflammation, and consider how they might be used to guide specific treatments.
60 Citations Source Cite
Published on Jan 1, 2017in Journal of Gastroenterology and Hepatology 3.48
Fan Wang6
Estimated H-index: 6
(WHU: Wuhan University),
Xue Lin3
Estimated H-index: 3
(WHU: Wuhan University)
+ 1 AuthorsJinLi16
Estimated H-index: 16
(WHU: Wuhan University)
Background and Aim Fat intake is generally thought as a risk factor for onset of ulcerative colitis (UC), while epidemiological data had been controversial. This study aimed to evaluate the role of fat intake in the development of UC. Methods Comprehensive search in PubMed and Embase was conducted to identify all relevant studies, and the role of fat intake in the development of UC was quantitatively assessed by dose–response meta-analysis. Results Nine studies (four case–control and five prospe...
7 Citations Source Cite
Published on Sep 1, 2016in Arteriosclerosis, Thrombosis, and Vascular Biology 6.09
Jaike Praagman3
Estimated H-index: 3
Ester Al de Jonge7
Estimated H-index: 7
+ 6 AuthorsOscar H. Franco74
Estimated H-index: 74
Objective— We assessed whether the association between dietary saturated fatty acids (SFA) and incident coronary heart disease (CHD) depends on the food source, the carbon chain length of SFA, and the substituting macronutrient. Approach and Results— From the Rotterdam Study, 4722 men and women (≥55 years) were included. Baseline (1990–1993) SFA intake was assessed using a validated food frequency questionnaire. CHD (nonfatal myocardial infarction and fatal CHD) was ascertained by medical record...
16 Citations Source Cite
Published on Aug 1, 2016in JAMA Internal Medicine 19.99
Dong D. Wang19
Estimated H-index: 19
(Harvard University),
Yanping Li43
Estimated H-index: 43
(Harvard University)
+ 5 AuthorsFrank B. Hu202
Estimated H-index: 202
(Harvard University)
Importance Previous studies have shown distinct associations between specific dietary fat and cardiovascular disease. However, evidence on specific dietary fat and mortality remains limited and inconsistent. Objective To examine the associations of specific dietary fats with total and cause-specific mortality in 2 large ongoing cohort studies. Design, Setting, and Participants This cohort study investigated 83 349 women from the Nurses’ Health Study (July 1, 1980, to June 30, 2012) and 42 884 me...
117 Citations Source Cite
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