The transgenerational effects of oocyte mitochondrial supplementation
Abstract
Many women suffer from either failed fertilisation or their embryos arrest early during development. Autologous mitochondrial supplementation has been proposed as an assisted reproductive technology to overcome these problems. However, its safety remains to be tested in an animal model to determine if there are transgenerational effects. We have supplemented oocytes with autologous populations of mitochondria to generate founders. We mated the...
Paper Details
Title
The transgenerational effects of oocyte mitochondrial supplementation
Published Date
Apr 30, 2019
Journal
Volume
9
Issue
1
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