Early life stress alters transcriptomic patterning across reward circuitry in male and female mice

Pages: 624353
Published: May 2, 2019
Abstract
null Abuse, neglect, and other forms of early life stress (ELS) significantly increase risk for psychiatric disorders including depression. In this study, we show that ELS in a postnatal sensitive period increases sensitivity to adult stress in female mice, consistent with our earlier findings in male mice. We used RNA-sequencing in the ventral tegmental area, nucleus accumbens, and prefrontal cortex of male and female mice to show that adult...
Paper Details
Title
Early life stress alters transcriptomic patterning across reward circuitry in male and female mice
Published Date
May 2, 2019
Journal
Pages
624353
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