Enhancement of Binding Affinity of Folate to Its Receptor by Peptide Conjugation
Volume: 20, Issue: 9, Pages: 2152 - 2152
Published: Apr 30, 2019
Abstract
(1) Background: The folate receptor (FR) is a target for cancer treatment and detection. Expression of the FR is restricted in normal cells but overexpressed in many types of tumors. Folate was conjugated with peptides for enhancing binding affinity to the FR. (2) Materials and Methods: For conjugation, folate was coupled with propargyl or dibenzocyclooctyne, and 4-azidophenylalanine was introduced in peptides for "click" reactions. We measured...
Paper Details
Title
Enhancement of Binding Affinity of Folate to Its Receptor by Peptide Conjugation
Published Date
Apr 30, 2019
Volume
20
Issue
9
Pages
2152 - 2152
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