XPO1 Expression Is a Poor-Prognosis Marker in Pancreatic Adenocarcinoma
Abstract
Pancreatic adenocarcinoma (PAC) is one of the most aggressive human cancers and new systemic therapies are urgently needed. Exportin-1 (XPO1), which is a member of the importin-β superfamily of karyopherins, is the major exporter of many tumor suppressor proteins that are involved in the progression of PAC. Promising pre-clinical data using XPO1 inhibitors have been reported in PAC, but very few data are available regarding XPO1 expression in...
Paper Details
Title
XPO1 Expression Is a Poor-Prognosis Marker in Pancreatic Adenocarcinoma
Published Date
Apr 30, 2019
Journal
Volume
8
Issue
5
Pages
596 - 596
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History