Sex modulates hepatic mitochondrial adaptations to high-fat diet and physical activity

Volume: 317, Issue: 2, Pages: E298 - E311
Published: Aug 1, 2019
Abstract
The impact of sexual dimorphism and mitophagy on hepatic mitochondrial adaptations during the treatment of steatosis with physical activity are largely unknown. Here, we tested if deficiencies in liver-specific peroxisome proliferative activated-receptor-γ coactivator-1α (PGC-1α), a transcriptional coactivator of biogenesis, and BCL-2/ADENOVIRUS EIB 19-kDa interacting protein (BNIP3), a mitophagy regulator, would impact hepatic mitochondrial...
Paper Details
Title
Sex modulates hepatic mitochondrial adaptations to high-fat diet and physical activity
Published Date
Aug 1, 2019
Volume
317
Issue
2
Pages
E298 - E311
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