Multiple particle tracking in time-lapse synchrotron X-ray images using discriminative appearance and neighbouring topology learning

Recent research has introduced a novel method of directly monitoring the effects of potential therapies for Cystic Fibrosis (CF) airway disease by quantifying mucociliary transit (MCT). In this method, micron-sized spherical particles are deposited into rodent airways, and synchrotron X-ray images are obtained to quantify the motion of the particles. However, the accurate tracking of these particles is challenging due to low contrast, image...