A combined FSTRA-shotgun proteomics approach to identify molecular changes in zebrafish upon chemical exposure

Volume: 9, Issue: 1
Published: Apr 29, 2019
Abstract
The fish short-term reproduction assay (FSTRA) is a common in vivo screening assay for assessing endocrine effects of chemicals on reproduction in fish. However, the current reliance on measures such as egg number, plasma vitellogenin concentration and morphological changes to determine endocrine effects can lead to false labelling of chemicals with non-endocrine modes- of-action. Here, we integrated quantitative liver and gonad shotgun...
Paper Details
Title
A combined FSTRA-shotgun proteomics approach to identify molecular changes in zebrafish upon chemical exposure
Published Date
Apr 29, 2019
Volume
9
Issue
1
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