A Catalase-Like Metal-Organic Framework Nanohybrid for O 2 -Evolving Synergistic Chemoradiotherapy.

Volume: 58, Issue: 26, Pages: 8752 - 8756
Published: Jun 24, 2019
Abstract
Tumor hypoxia, the Achilles' heel of current cancer therapies, is indispensable to drug resistance and poor therapeutic outcomes especially for radiotherapy. Here we propose an in situ catalytic oxygenation strategy in tumor using porphyrinic metal-organic framework (MOF)-gold nanoparticles (AuNPs) nanohybrid as a therapeutic platform to achieve O2 -evolving chemoradiotherapy. The AuNPs decorated on the surface of MOF effectively stabilize the...
Paper Details
Title
A Catalase-Like Metal-Organic Framework Nanohybrid for O 2 -Evolving Synergistic Chemoradiotherapy.
Published Date
Jun 24, 2019
Volume
58
Issue
26
Pages
8752 - 8756
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