Effects of interleukin-1 antagonism on cortisol levels in individuals with obesity: a randomized clinical trial

Volume: 8, Issue: 6, Pages: 701 - 708
Published: Jun 1, 2019
Abstract
Background Anti-inflammatory treatment with interleukin-1 (IL-1) antagonism decreases both cortisol and adrenocorticotropin hormone (ACTH) levels in individuals with obesity in short term. However, it remains unknown whether these effects persist upon prolonged treatment. Methods In this double-blind, parallel-group trial involving patients with features of the metabolic syndrome, 33 patients were randomly assigned to receive 100 mg of anakinra...
Paper Details
Title
Effects of interleukin-1 antagonism on cortisol levels in individuals with obesity: a randomized clinical trial
Published Date
Jun 1, 2019
Volume
8
Issue
6
Pages
701 - 708
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