Original paper
Nuclear delivery of plasmid DNA determines the efficiency of gene expression
Abstract
As a cationic non‐viral gene delivery vector, poly(agmatine/ N , N ′‐cystamine‐bis‐acrylamide) (AGM‐CBA) showed significantly higher plasmid DNA (pDNA) transfection ability than polyethylenimine (PEI) in NIH/3T3 cells. The transfection expression of AGM‐CBA/pDNA polyplexes was found to have a non‐linear relationship with AGM‐CBA/pDNA weight ratios. To further investigate the mechanism involved in the transfection process of poly(AGM‐CBA), we...
Paper Details
Title
Nuclear delivery of plasmid DNA determines the efficiency of gene expression
Published Date
May 18, 2019
Journal
Volume
43
Issue
7
Pages
789 - 798
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Notes
History