<p>Mutation spectrum of germline cancer susceptibility genes among unselected Chinese colorectal cancer patients</p>
Abstract
Background: Genetic factors play an important role in colorectal cancer (CRC) risk, yet the prevalence and spectrum of germline cancer susceptibility gene mutations among unselected Chinese CRC patients is largely undetermined. Methods: We performed next-generation sequencing with a 73-genes panel and analyzed the prevalence and spectrum of germline mutations in 618 unselected Chinese CRC patients. We classified all identified germline...
Paper Details
Title
<p>Mutation spectrum of germline cancer susceptibility genes among unselected Chinese colorectal cancer patients</p>
Published Date
Apr 1, 2019
Volume
Volume 11
Pages
3721 - 3739
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