Antioxidant and Anti-Diabetic Functions of a Polyphenol-Rich Sugarcane Extract.
Published on Apr 22, 2019in Journal of The American College of Nutrition2.08
· DOI :10.1080/07315724.2019.1587323
AbstractObjectives: Dysfunctional metabolism of carbohydrates is a fundamental component of many dietary-related disorders. It has been hypothesized that plant extracts containing high levels of antioxidants may have the ability to stabilize carbohydrate regulation. The aim of this study was to assess the effects of a polyphenol-rich sugarcane extract on cellular pathways related to carbohydrate metabolism.Methods: We evaluated the antioxidant activity of a polyphenol-rich sugarcane extract obtained by a patented hydrophobic extract process and its therapeutic potential to regulate carbohydrate metabolism and protect against metabolic disorders such as type 2 diabetes.Results: Quantitative analytical studies support that the polyphenol-rich sugarcane extract has a high concentration of polyphenols and antioxidant compounds. The follow-up cellular studies via Caco-2 cells and dysfunctional β-cell models suggested that the polyphenol-rich sugarcane extract may help deter glucose and fructose uptake in intes...