A (fire)cloud-based DNA methylation data preprocessing and quality control platform

Bisulfite sequencing allows base-pair resolution profiling of DNA methylation and has recently been adapted for use in single-cells. Analyzing these data, including making comparisons with existing data, remains challenging due to the scale of the data and differences in preprocessing methods between published datasets. We present a set of preprocessing pipelines for bisulfite sequencing DNA methylation data that include a new R/Bioconductor...