Influence of blood pressure on the effects of low-dose asprin in elderly patients with multiple atherosclerotic risks

Objective: We examined whether the efficacy of low-dose acetylsalicylic acid (aspirin) for primary prevention of cardiovascular events is influenced by blood pressure (BP) using data from patients aged 60–85 years with hypertension, dyslipidemia, and/or diabetes, but without cardiovascular disease of the Japanese Primary Prevention Project. Methods: All patients had received aspirin (100 mg/day) or no aspirin. BP subgroups were defined as low...