Sex differences in the expression of calcitonin gene-related peptide receptor components in the spinal trigeminal nucleus
Abstract
Calcitonin gene-related peptide (CGRP) plays an important role in migraine pathophysiology. CGRP acts primarily by activating a receptor composed of 3 proteins: calcitonin receptor-like receptor (CLR), receptor activity-modifying protein 1 (RAMP1), and receptor component protein (RCP). We tested the hypothesis that sex differences exist in protein levels of two key components of this CGRP receptor: CLR and RCP.We used specific antibodies to...
Paper Details
Title
Sex differences in the expression of calcitonin gene-related peptide receptor components in the spinal trigeminal nucleus
Published Date
Aug 1, 2019
Journal
Volume
6
Pages
100031 - 100031
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