Pancreatic perfusion and its response to glucose as measured by simultaneous PET/MRI

Perfusion of the pancreas and the islets of Langerhans is sensitive to physiological stimuli and is dysregulated in metabolic disease. Pancreatic perfusion can be assessed by both positron emission tomography (PET) and magnetic resonance imaging (MRI), but the methods have not been directly compared or benchmarked against the gold-standard microsphere technique.Pigs (n = 4) were examined by [15O]H2O PET and intravoxel incoherent motion (IVIM)...