The autoimmune targets in IPEX are dominated by gut epithelial proteins
Volume: 144, Issue: 1, Pages: 327 - 330.e8
Published: Jul 1, 2019
Abstract
Regulatory T (Treg) cells play a key role in immune system homeostasis by suppressing detrimental immune responses against self-proteins, in particular in the intestine.1Tanoue T. Atarashi K. Honda K. Development and maintenance of intestinal regulatory T cells.Nat Rev Immunol. 2016; 16: 295-309Crossref PubMed Scopus (277) Google Scholar Patients with mutations in the gene FOXP3 display a severe defect of Treg-cell function that results in IPEX...
Paper Details
Title
The autoimmune targets in IPEX are dominated by gut epithelial proteins
Published Date
Jul 1, 2019
Volume
144
Issue
1
Pages
327 - 330.e8
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