Transcutaneous carbon dioxide application inhibits muscle atrophy after fracture in rats

Muscle atrophy causes difficulty in resuming daily activities after a fracture. Because transcutaneous carbon dioxide (CO2) application has previously upregulated oxygen pressure in the local tissue, thereby demonstrating its potential in preventing muscle atrophy, here we investigated effects of CO2 application on muscle atrophy after femoral shaft fracture. Thirty fracture model rats were produced and randomly divided into a no treatment...