Derivation of adult canine intestinal organoids for translational research in gastroenterology

Volume: 17, Issue: 1
Published: Apr 11, 2019
Abstract
Large animal models, such as the dog, are increasingly being used for studying diseases including gastrointestinal (GI) disorders. Dogs share similar environmental, genomic, anatomical, and intestinal physiologic features with humans. To bridge the gap between commonly used animal models, such as rodents, and humans, and expand the translational potential of the dog model, we developed a three-dimensional (3D) canine GI organoid (enteroid and...
Paper Details
Title
Derivation of adult canine intestinal organoids for translational research in gastroenterology
Published Date
Apr 11, 2019
Volume
17
Issue
1
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