Clinical Outcomes of Lung Transplantation in the Presence of Donor-Specific Antibodies

Rationale: There is significant variation in approach to pre–lung transplant donor-specific antibodies (DSA), with some centers declining to cross any DSA. We implemented a protocol for transplantation for candidates with pretransplant DSA so long as a prospective complement-dependent cytotoxicity crossmatch was negative, regardless of number, specificity, class, or mean fluorescence intensity.Objectives: To compare post-transplant outcomes...