Confinement and reversibility of threshold-dependent gene drive systems in spatially-explicit Aedes aegypti populations

Pages: 607267
Published: Apr 12, 2019
Abstract
null Background null The discovery of CRISPR-based gene editing and its application to homing-based gene drive systems has been greeted with excitement, for its potential to control mosquito-borne diseases on a wide scale, and concern, for the invasiveness and potential irreversibility of a release. Gene drive systems that display threshold-dependent behavior could potentially be used during the trial phase of this technology, or when localized...
Paper Details
Title
Confinement and reversibility of threshold-dependent gene drive systems in spatially-explicit Aedes aegypti populations
Published Date
Apr 12, 2019
Journal
Pages
607267
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