Synthesis, characterization, DNA binding and cleaving properties of photochemically activated phenanthrene dihydrodioxin

Volume: 380, Pages: 111803
Published: Jul 1, 2019
Abstract
null null Dihydrodioxin compounds are formed upon visible light irradiation of a mixture of an ortho-quinone and a substituted alkene. The reverse photochemical reaction can result in the release of a highly reactive ortho-quinone that can induce oxidative DNA damage. A novel DNA binding and cleaving phenanthrene dihydrodioxin compound (1) was synthesized. The photochemical release of 9,10-phenanthrenequinone was studied under different light...
Paper Details
Title
Synthesis, characterization, DNA binding and cleaving properties of photochemically activated phenanthrene dihydrodioxin
Published Date
Jul 1, 2019
Volume
380
Pages
111803
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