Development of blastocyst complementation technology without contributions to gametes and the brain.
Abstract
In Japan, it is possible to generate chimeric animals from specified embryos by combining animal blastocysts with human pluripotent stem (PS) cells (animal-human PS chimera). However, the production of animal-human PS chimeras has been restricted because of ethical concerns, such as the development of human-like intelligence and formation of humanized gametes in the animals, owing to the contributions of human PS cells to the brain and...
Paper Details
Title
Development of blastocyst complementation technology without contributions to gametes and the brain.
Published Date
Apr 17, 2019
Journal
Volume
68
Issue
3
Pages
361 - 370
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Notes
History