Genetic risk scores demonstrate the cumulative association of single nucleotide polymorphisms in gut microbiome‐related genes with obesity phenotypes in preschool age children

Summary Background Childhood obesity is a nutrition‐related disease with multiple underlying aetiologies. While genetic factors contribute to obesity, the gut microbiome is also implicated through fermentation of nondigestible polysaccharides to short‐chain fatty acids (SCFA), which provide some energy to the host and are postulated to act as signalling molecules to affect expression of gut hormones. Objective To study the cumulative association...