An open-label, randomized phase III study of early switch maintenance vs delayed second-line nivolumab in advanced stage squamous non-small cell lung cancer (NSCLC) patients after standard first-line platinum-based chemotherapy: EDEN trial
Abstract
Background: Squamous non-small cell lung cancer (Sq-NSCLC) represents 20-30% of all NSCLC with a disappointing median overall survival (OS). In the last decades, first-line chemotherapy (Ctx) for advanced Sq-NSCLC has not changed and the standard of care remains a platinum-based regimen (cisplatin or carboplatin) combined with gemcitabine, vinorelbine or taxanes for up to 4-6 cycles. In non-squamous NSCLC, maintenance therapy (MTx) by continuing...
Paper Details
Title
An open-label, randomized phase III study of early switch maintenance vs delayed second-line nivolumab in advanced stage squamous non-small cell lung cancer (NSCLC) patients after standard first-line platinum-based chemotherapy: EDEN trial
Published Date
Apr 1, 2019
Journal
Volume
30
Pages
ii67 - ii68
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Notes
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