Original paper
High Body Mass Index is Associated with Elevated Blood Levels of Progerin mRNA
Volume: 20, Issue: 8, Pages: 1976 - 1976
Published: Apr 23, 2019
Abstract
Obesity is a well-described risk factor resulting in premature aging of the cardiovascular system ultimately limiting longevity. Premature cardiac death and aging is the hallmark of Hutchinson–Gilford syndrome (HGPS), a disease caused by defined mutations in the lamin A gene leading to a shortened prelamin A protein known as progerin. Since small amounts of progerin are expressed in healthy individuals we aimed to investigate the association of...
Paper Details
Title
High Body Mass Index is Associated with Elevated Blood Levels of Progerin mRNA
Published Date
Apr 23, 2019
Volume
20
Issue
8
Pages
1976 - 1976
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Notes
History