Original paper
The interplay of circulating tumor DNA and chromatin modification, therapeutic resistance, and metastasis
Abstract
Peripheral circulating free DNA (cfDNA) is DNA that is detected in plasma or serum fluid with a cell-free status. For cancer patients, cfDNA not only originates from apoptotic cells but also from necrotic tumor cells and disseminated tumor cells that have escaped into the blood during epithelial-mesenchymal transition. Additionally, cfDNA derived from tumors, also known as circulating tumor DNA (ctDNA), carries tumor-associated genetic and...
Paper Details
Title
The interplay of circulating tumor DNA and chromatin modification, therapeutic resistance, and metastasis
Published Date
Mar 9, 2019
Journal
Volume
18
Issue
1
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Notes
History