Original paper

The interplay of circulating tumor DNA and chromatin modification, therapeutic resistance, and metastasis

Volume: 18, Issue: 1
Published: Mar 9, 2019
Abstract
Peripheral circulating free DNA (cfDNA) is DNA that is detected in plasma or serum fluid with a cell-free status. For cancer patients, cfDNA not only originates from apoptotic cells but also from necrotic tumor cells and disseminated tumor cells that have escaped into the blood during epithelial-mesenchymal transition. Additionally, cfDNA derived from tumors, also known as circulating tumor DNA (ctDNA), carries tumor-associated genetic and...
Paper Details
Title
The interplay of circulating tumor DNA and chromatin modification, therapeutic resistance, and metastasis
Published Date
Mar 9, 2019
Volume
18
Issue
1
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