Next generation sequencing of PD-L1 for predicting response to immune checkpoint inhibitors

Volume: 7, Issue: 1, Pages: 18 - 18
Published: Jan 24, 2019
Abstract
PD-L1 immunohistochemistry (IHC) has been traditionally used for predicting clinical responses to immune checkpoint inhibitors (ICIs). However, there are at least 4 different assays and antibodies used for PD-L1 IHC, each developed with a different ICI. We set to test if next generation RNA sequencing (RNA-seq) is a robust method to determine PD-L1 mRNA expression levels and furthermore, efficacy of predicting response to ICIs as compared to...
Paper Details
Title
Next generation sequencing of PD-L1 for predicting response to immune checkpoint inhibitors
Published Date
Jan 24, 2019
Volume
7
Issue
1
Pages
18 - 18
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