Clinical-like cryotherapy improves gait function and reduces synovial inflammation in rats with knee osteoarthritis

Purpose: To evaluate the effects of clinical-like cryotherapy on gait function and synovial inflammation in rats with knee osteoarthritis (KOA) induced by anterior cruciate ligament transection (ACLT). Methods: The experimental protocol was in accordance with the National Guide for the Care and Use of Laboratory Animals (National Research Council, 1996). All procedures were approved by the institutional Ethics Committee and conducted by trained...