Differential effects of neurodegeneration biomarkers on subclinical cognitive decline

Volume: 5, Issue: 1, Pages: 129 - 138
Published: Jan 1, 2019
Abstract
Introduction Neurodegeneration appears to be the biological mechanism most proximate to cognitive decline in Alzheimer's disease. We test whether t-tau and alternative biomarkers of neurodegeneration—neurogranin and neurofilament light protein (NFL)—add value in predicting subclinical cognitive decline. Methods One hundred fifty cognitively unimpaired participants received a lumbar puncture for cerebrospinal fluid and at least two...
Paper Details
Title
Differential effects of neurodegeneration biomarkers on subclinical cognitive decline
Published Date
Jan 1, 2019
Volume
5
Issue
1
Pages
129 - 138
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