Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood

Cell64.50
Volume: 177, Issue: 3, Pages: 587
Published: Apr 18, 2019
Abstract
Severe obesity is a rapidly growing global health threat. Although often attributed to unhealthy lifestyle choices or environmental factors, obesity is known to be heritable and highly polygenic; the majority of inherited susceptibility is related to the cumulative effect of many common DNA variants. Here we derive and validate a new polygenic predictor comprised of 2.1 million common variants to quantify this susceptibility and test this...
Paper Details
Title
Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood
Published Date
Apr 18, 2019
Journal
Volume
177
Issue
3
Pages
587
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