Programming of ES cells and reprogramming of fibroblasts into renal lineage-like cells.
Abstract
This study aims to prepare intermediate mesoderm-like cells from mouse embryonic fibroblasts (MEFs). In the first step, intermediate mesoderm-like cells (IMLCs) and renal epithelial-like cells (RELCs) were extracted from mouse embryonic stem cells (mESCs) in a specified media that contained two small molecules, CHIR99021 and TTNPB, along with growth factors, FGF9and BMP7. Then, MEFs were directly converted into IM by genes for the pluripotency...
Paper Details
Title
Programming of ES cells and reprogramming of fibroblasts into renal lineage-like cells.
Published Date
Jun 15, 2019
Journal
Volume
379
Issue
2
Pages
225 - 234
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Notes
History