Functioning of Mycobacterial Heat Shock Repressors Requires the Master Virulence Regulator PhoP
Abstract
A hallmark feature of Mycobacterium tuberculosis pathogenesis lies in the ability of the pathogen to survive within macrophages under a stressful environment. Thus, coordinated regulation of stress proteins is critically important for an effective adaptive response of M. tuberculosis, the failure of which results in elevated immune recognition of the tubercle bacilli with reduced survival during chronic infections. Here, we show that virulence...
Paper Details
Title
Functioning of Mycobacterial Heat Shock Repressors Requires the Master Virulence Regulator PhoP
Published Date
Jun 15, 2019
Journal
Volume
201
Issue
12
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Notes
History