Nano-GLADIATOR: real-time detection of copy number alterations from nanopore sequencing data
Abstract
Motivation The past few years have seen the emergence of nanopore-based sequencing technologies which interrogate single molecule of DNA and generate reads sequentially. Results In this paper, we demonstrate that, thanks to the sequentiality of the nanopore process, the data generated in the first tens of minutes of a typical MinION/GridION run can be exploited to resolve the alterations of a human genome at a karyotype level with a resolution...
Paper Details
Title
Nano-GLADIATOR: real-time detection of copy number alterations from nanopore sequencing data
Published Date
Apr 5, 2019
Journal
Volume
35
Issue
21
Pages
4213 - 4221
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