Smooth Muscle Relaxant Triterpenoid Glycosides from Rubus idaeus (Raspberry) Leaves

A methanol extract of Rubus idaeus leaves had a relaxant activity on transmurally stimulated Guinea pig ileum preparations in vitro. The extract, when fractionated by column chromatography, yielded two distinct bands with pharmacological activity. After extensive column and preparative TLC separation, several compounds with smooth muscle relaxant properties were obtained. From band two, three triterpenoid glycosides were characterized, which had...