Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction

Volume: 18, Issue: 3
Published: Mar 28, 2019
Abstract
Cardiovascular disease is the leading cause of death in individuals over 60 years old. Aging is associated with an increased prevalence of coronary artery disease and a poorer prognosis following acute myocardial infarction (MI). With age, senescent cells accumulate in tissues, including the heart, and contribute to age‐related pathologies. However, the role of senescence in recovery following MI has not been investigated. In this study, we...
Paper Details
Title
Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction
Published Date
Mar 28, 2019
Journal
Volume
18
Issue
3
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