Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine
Abstract
To identify a plasma metabolomic biomarker signature for migraine.Plasma samples from 8 Dutch cohorts (n = 10,153: 2,800 migraine patients and 7,353 controls) were profiled on a 1H-NMR-based metabolomics platform, to quantify 146 individual metabolites (e.g., lipids, fatty acids, and lipoproteins) and 79 metabolite ratios. Metabolite measures associated with migraine were obtained after single-metabolite logistic regression combined with a...
Paper Details
Title
Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine
Published Date
Apr 16, 2019
Journal
Volume
92
Issue
16
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