Single-cell transcriptomics of the naked mole-rat reveals unexpected features of mammalian immunity

Abstract
Using single-cell transcriptional profiling we mapped the immune system of the naked mole-rat ( Heterocephalus glaber ), a small but long-lived and cancer-resistant subterranean rodent. Both splenic and circulating immune cells were examined in healthy young animals and following an infection-mimicking lipopolysaccharide challenge. Our study revealed that the naked mole-rat immune system is characterized by a high myeloid to lymphoid cell ratio...
Paper Details
Title
Single-cell transcriptomics of the naked mole-rat reveals unexpected features of mammalian immunity
Published Date
Apr 4, 2019
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.