Sitting time and all-cause and cardiovascular mortality risk among 149,077 adults: what is the role of physical activity?

Background: It is less clear what level of moderate to vigorous intensity physical activity (MVPA) offsets the health risks of sitting. Objectives: to examine the joint and stratified associations of sitting and MVPA with all-cause and cardiovascular disease (CVD) mortality; and to estimate the theoretical effect of replacing sitting time with physical activity, standing, and sleep. Methods: Longitudinal analysis of the 45 and Up Study to...