Enhanced in vivo Optical Imaging of the Inflammatory Response to Acute Liver Injury in C57BL/6 Mice Using a Highly Bright Near‐Infrared BODIPY Dye

Delving deeper is possible in whole‐body in vivo imaging using a super‐bright membrane‐targeting BODIPY dye ( BD ). The dye was used to monitor homing of ex vivo fluorescently labelled neutrophils to an injured liver of dark‐pigmented C57BL/6 mice. In vivo imaging system (IVIS) data conclusively showed an enhanced signal intensity and a higher signal‐to‐noise ratio in mice receiving neutrophils labelled with the BD dye relative to those labelled...