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doi.org/10.1016/j.phrs.2019.04.008

Mitochondrial DNA: A new driver for sex differences in spontaneous hypertension

..., Maria Helena Catelli de Carvalho
41
Pharmacological Research9.30
Volume: 144, Pages: 142 - 150
Published: Jun 1, 2019
Abstract
The prevalence of arterial hypertension (AH) is higher in men than in premenopausal women of the same age. AH has been characterized as a chronic inflammatory disease and activation of Toll-like receptors (TLR) by damage-associated molecular patterns (DAMPs) is involved. Mitochondrial DNA (mtDNA) may be released by end-organ damage, which is recognized and activates TLR9. The serum level of mtDNA is increased in AH. The aim of this study was to...
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Paper Details
Title
Mitochondrial DNA: A new driver for sex differences in spontaneous hypertension
DOI
doi.org/10.1016/j.phrs.2019.04.008
Published Date
Jun 1, 2019
Journal
Pharmacological Research
Volume
144
Pages
142 - 150
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