Exogenous Vasohibin-2 Exacerbates Angiotensin II-Induced Ascending Aortic Dilation in Mice
Abstract
Background: Chronic angiotensin II (AngII) infusion promotes ascending aortic dilation in C57BL/6J mice. Meanwhile, vasohibin-2 (VASH2) is an angiogenesis promoter in neovascularization under various pathologic conditions. The aim of this study was to investigate whether exogenous VASH2 influences chronic AngII-induced ascending aortic dilation.
Methods and Results: Eight–ten-week-old male C57BL/6J mice were injected with adenovirus (Ad)...
Paper Details
Title
Exogenous Vasohibin-2 Exacerbates Angiotensin II-Induced Ascending Aortic Dilation in Mice
Published Date
Apr 10, 2019
Journal
Volume
1
Issue
4
Pages
155 - 161
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