Arctigenin improves lipid metabolism by regulating AMP‐activated protein kinase and downstream signaling pathways

Although it has been reported that arctigenin (ARG) can reduce the body weight and inhibit adipogenic differentiation by activating AMP‐activated protein kinase (AMPK), the exact signals responsible for the ARG‐mediated antiobesity mechanism through AMPK are not well understood. In this study, we investigated the potential improvement of AGR on lipid metabolism using a high‐fat diet (HFD)‐induced hyperlipidemia rats and 3T3‐L1 mature adipocytes....