Alteration of gut microbiota induced by DPP-4i treatment improves glucose homeostasis
Abstract
BackgroundIncreasing evidence indicates that the gut microbiota contributes to the occurrence and development of metabolic diseases. However, little is known about the effects of commonly used antidiabetic agents on the gut microbiota. In this study, we investigated the roles of dipeptidyl peptidase-4 inhibitors (DPP-4i) and α-glucosidase inhibitor in modulating the gut microbiota.Methods16S-rDNA sequencing was performed to analyse the effects...
Paper Details
Title
Alteration of gut microbiota induced by DPP-4i treatment improves glucose homeostasis
Published Date
Jun 1, 2019
Journal
Volume
44
Pages
665 - 674
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